Caries vaccine: current reality or remote future?
نویسندگان
چکیده
Dental caries remains a public health problem in developing countries requiring effective strategies to combat this disease. Caries vaccines showed promising results in experimental studies; however, it remains far the effective use in humans due to political-economic and ethical issues. The purpose of this chapter is to review the literature on the main research projects aimed at developing caries vaccines. The following topics will be covered: virulence and cariogenicity of Streptococcus mutans, caries vaccine, animal models for testing caries vaccines, caries vaccine types, and replacement or substitution therapy and future prospects.
منابع مشابه
The Comparison of Proteins Elaborated by Streptococcus mutans Strains Isolated from Caries Free and Susceptible Subjects
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